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Inside Madhuri Dixit and Dr. Nene's marriage and love: He was among America's top doctors but when she was sick, he was mostly away

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Madhuri Dixit and her husband, Dr. Sriram Nene, frequently open up about their family life on his YouTube platform. In one candid episode, Madhuri acknowledged that their marital journey hasn’t always been smooth, describing it as a blend of trials and joy.

She revealed that during the more demanding periods—especially when Dr. Nene was consumed by work for extended durations—she managed the household responsibilities on her own. However, she emphasized that her husband always made an effort to share the domestic load whenever he was free. Madhuri added that, had she pursued medicine as a profession, she likely would have done the same. She believes their work ethic has positively influenced their children.

Dr. Nene added a humorous perspective, saying, “When heart surgeons retire, their wives tend to send them out of the house because they start organizing every drawer and streamlining every system.”

Recalling their early married life, Madhuri spoke about the initial years when Dr. Nene was completing his medical residency in Florida. She remembered the irregular contact and long stretches without seeing him. “You’d be working all night and return home completely exhausted, sometimes skipping meals and just collapsing into bed,” she said.

Dr. Nene elaborated on the intensity of the medical profession in the United States, calling it a test of physical and emotional stamina. “To become a doctor in the U.S., you go through four years of undergraduate studies, complete your pre-med requirements, excel in competitive exams, then spend another four years in medical school. When we married, I had just finished my chief residency in general surgery at UCLA and was preparing for our move to Florida. The schedule was grueling, but it built mental toughness. I thought residency and fellowship were tough, but being an attending physician was even harder because you carry full responsibility.”

While he doesn’t lament the effort he invested in his career, he admitted, “I do feel the loss of time I could’ve spent with loved ones.”

When he asked Madhuri what it was like being married to someone with such a demanding profession, she responded honestly. “It was difficult. The odd hours, managing the kids, school runs—all on my own sometimes. There were moments when you were absent during important family events or when I was unwell. But I was always proud of you. You’re kind at heart. And when you were home, you never hesitated to take over. You’d just ask for a few hours of rest and then tell me to take a break.”

Madhuri concluded by saying, “Before marriage, my world revolved around work. Marriage gave me a fuller life.” The couple married in 1999 and are now based in India with their two sons.
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